Over at his blog, Mike Jasper has an excellent post on the hows of setting up In Maps & Legends as a digital comic. It’s an excellent point for any budding independent creator to look at!
In particular, we’ve had great success working with Comixology and Graphic.ly, who have become the pioneers and big guns of distributing digital comics (and they’ve been nothing but incredible to work with). I highly recommend getting your digital comics online with them — they’re fine people, and they seem especially open to creator-owned comics.
We’ve also been pleasantly surprised by the success we’ve had selling PDFs withDriveThruComics, a great site with tons of comics and a great, easy-to-use interface for uploading comics, doing promotional work, and tracking your sales in real time. That last one is huge.